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(B) The target compound is $1-tert-butyl-4-nitrobenzene$. First,we perform a Friedel-Crafts alkylation on benzene using $tert-butyl$ chloride $(Me_3CC

Vedclass · Accepted Answer

Benzene $\xrightarrow{(1) Me_3CCl/AlCl_3}$ $\xrightarrow{(2) HNO_3/H_2SO_4}$

Vedclass · Answer

(B) The target compound is $1-tert-butyl-4-nitrobenzene$. First,we perform a Friedel-Crafts alkylation on benzene using $tert-butyl$ chloride $(Me_3CCl)$ and $AlCl_3$ to form $tert-butylbenzene$. Then,we perform nitration using a mixture of concentrated $HNO_3$ and $H_2SO_4$. Since the $tert-butyl$ group is an ortho/para-directing group and is bulky,the para-isomer is the major product due to steric hindrance at the ortho position. Therefore,the correct sequence is: $1$. Friedel-Crafts alkylation with $Me_3CCl/AlCl_3$. $2$. Nitration with $HNO_3/H_2SO_4$.

Choose the best method to prepare the given compound:

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