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(A) Beadle and Tatum proposed the 'one gene-one enzyme' hypothesis based on their experiments with the bread mold $Neurospora crassa$.They demonstrate

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One gene produces one enzyme

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(A) Beadle and Tatum proposed the 'one gene-one enzyme' hypothesis based on their experiments with the bread mold $Neurospora crassa$.They demonstrated that specific mutations in genes resulted in the loss of specific enzymatic activities, thereby proving that a single gene is responsible for the synthesis of a single specific enzyme (or protein).

Beadle and $E.L. Tatum$ performed a classical experiment on $Neurospora crassa$ to explain:

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