At which stage of the cell cycle does colchic | vedclass

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Question

(D) Colchicine is an antimitotic drug (alkaloid) obtained from $Colchicum$ (family $Liliaceae$).It binds to tubulin molecules and prevents their polym

Vedclass · Accepted Answer

Metaphase

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(D) Colchicine is an antimitotic drug (alkaloid) obtained from $Colchicum$ (family $Liliaceae$).It binds to tubulin molecules and prevents their polymerization into microtubules.The depolymerization of tubulin leads to the disappearance of the mitotic spindle.As a result,the cell is unable to proceed from metaphase to anaphase,effectively arresting the cell cycle at the metaphase stage.

At which stage of the cell cycle does colchicine arrest the spindle?

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