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(B) The body's immune system is capable of differentiating between 'self' and 'non-self' cells. When an organ from an unrelated donor is transplanted,

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Cell-mediated immunity

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(B) The body's immune system is capable of differentiating between 'self' and 'non-self' cells. When an organ from an unrelated donor is transplanted,the recipient's immune system recognizes the foreign antigens on the donor tissue. Cell-mediated immunity,primarily involving $T$-lymphocytes,plays the lead role in graft rejection. These $T$-cells identify the foreign cells and initiate an immune response to destroy the transplanted tissue.

After an organ transplant from an unrelated donor,which of the following plays the lead role in graft rejection?

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