The conversion shown in the image can be achi | vedclass

Name: Exam Paper Generator | JEE NEET Paper Generator | Vedclass
Brand: Vedclass
Rating: 5 (35 reviews)

Question

(B) The reaction involves the reduction of a carbonyl group $(C=O)$ to a methylene group $(CH_2)$.$1$. Clemmensen reduction $(Zn(Hg), HCl)$ is acidic

Vedclass · Accepted Answer

$NH_2-NH_2/KOH/\Delta$

Vedclass · Answer

(B) The reaction involves the reduction of a carbonyl group $(C=O)$ to a methylene group $(CH_2)$.$1$. Clemmensen reduction $(Zn(Hg), HCl)$ is acidic and would hydrolyze the acetal/thioacetal protecting group.$2$. Wolff-Kishner reduction $(NH_2-NH_2/KOH/\Delta)$ is basic and is suitable for reducing carbonyls in the presence of base-stable protecting groups like acetals or thioacetals.$3$. $LiAlH_4$ would reduce the carbonyl to an alcohol.$4$. $H_2/Ni$ would reduce the carbonyl to an alcohol.Therefore,the correct reagent is $NH_2-NH_2/KOH/\Delta$.

The conversion shown in the image can be achieved by:

Similar Questions

Explain the cross aldol condensation reaction.

What is the number of different products formed when a mixture of ethanal and propanal reacts with aqueous $NaOH$ after warming?

The correct structure of product $A$ formed in the following reaction:
$PhCHO + PhCHO \xrightarrow[in\, D_2O]{NaOD} A + PhCOO^{-}$
($Ph$ is $-C_6H_5$)

The most appropriate reagent to distinguish between acetaldehyde and formaldehyde is

The reagent used in the Wolff-Kishner reduction is

Vedclass Test Series

Exam Paper Generator

Online Exam Module