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(D) The mathematical model describing the rate of enzymatic reactions by relating reaction rate $v$ to the concentration of a substrate $[S]$ was deve

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Leonor Michaelis and Maud Menten

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(D) The mathematical model describing the rate of enzymatic reactions by relating reaction rate $v$ to the concentration of a substrate $[S]$ was developed by Leonor Michaelis and Maud Menten in $1913$. This is known as the Michaelis-Menten kinetics,represented by the equation $v = \frac{V_{max}[S]}{K_m + [S]}$,where $V_{max}$ is the maximum velocity and $K_m$ is the Michaelis constant.

$A$ mathematical explanation of enzyme action on substrate was formulated by

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