What is the increasing order of reactivity of | vedclass

Name: Exam Paper Generator | JEE NEET Paper Generator | Vedclass
Brand: Vedclass
Rating: 5 (35 reviews)

Question

(A) Williamson synthesis proceeds via an $S_N2$ mechanism. The reactivity of alkyl halides in $S_N2$ reactions depends on steric hindrance and the nat

Vedclass · Accepted Answer

$III < IV < II < I$

Vedclass · Answer

(A) Williamson synthesis proceeds via an $S_N2$ mechanism. The reactivity of alkyl halides in $S_N2$ reactions depends on steric hindrance and the nature of the leaving group.$1$. Steric hindrance: Primary $(1^o)$ halides are more reactive than bulky ones. $III$ is a neopentyl bromide,which is highly sterically hindered,making it the least reactive.$2$. Leaving group: Bromide $(Br^-)$ is a better leaving group than chloride $(Cl^-)$.$3$. Allylic effect: Allyl halides $(I)$ are highly reactive in $S_N2$ reactions due to the resonance stabilization of the transition state.Comparing the given compounds:- $I$ $(CH_2=CHCH_2Cl)$: Allylic halide (highly reactive).- $II$ $(CH_3CH_2CH_2Br)$: $1^o$ bromide (good leaving group).- $IV$ $(CH_3CH_2CH_2Cl)$: $1^o$ chloride (poorer leaving group than $Br^-$).- $III$ $((CH_3)_3CCH_2Br)$: Sterically hindered $1^o$ bromide (neopentyl).The order of reactivity is $III < IV < II < I$.

What is the increasing order of reactivity of the following alkyl halides in the Williamson synthesis?
$I. \, CH_2 = CHCH_2Cl$
$II. \, CH_3CH_2CH_2Br$
$III. \, (CH_3)_3CCH_2Br$
$IV. \, CH_3CH_2CH_2Cl$

Similar Questions

Identify the major products $A$ and $B$ respectively in the following reactions of phenol.

For the compounds:
$(A)$ $H_3C-CH_2-O-CH_2-CH_2-CH_3$
$(B)$ $H_3C-CH_2-CH_2-CH_2-CH_3$
$(C)$ $CH_3-CH_2-CO-CH_2-CH_3$
$(D)$ $H_3C-CH(OH)-CH_2-CH_2-CH_3$
The increasing order of boiling point is:
Choose the correct answer from the options given below:

What is the product of the following reaction?

$HOOC-COOH + HO^{18}CH_2-CH_2^{18}OH \xrightarrow[H^+]{\Delta} (A)$; Product $(A)$ is:

In the reaction given below,identify the major product '$B$'.

Vedclass Test Series

Exam Paper Generator

Online Exam Module

What is the increasing order of reactivity of the following alkyl halides in the Williamson synthesis?$I. \, CH_2 = CHCH_2Cl$$II. \, CH_3CH_2CH_2Br$$III. \, (CH_3)_3CCH_2Br$$IV. \, CH_3CH_2CH_2Cl$