What is the priority order of the groups -OH, | vedclass

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(B) According to the $CIP$ priority rules,priority is assigned based on the atomic number of the atom directly attached to the chiral center.$1$. The

Vedclass · Accepted Answer

$OCH_3 > OH > CHO > COOH$

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(B) According to the $CIP$ priority rules,priority is assigned based on the atomic number of the atom directly attached to the chiral center.$1$. The atoms attached to the chiral carbon are $O$ (in $-OH$ and $-OCH_3$) and $C$ (in $-COOH$ and $-CHO$).$2$. Since the atomic number of $O$ $(8)$ is greater than $C$ $(6)$,$-OH$ and $-OCH_3$ have higher priority than $-COOH$ and $-CHO$.$3$. Comparing $-OH$ and $-OCH_3$: The $O$ in $-OCH_3$ is attached to a $C$ atom,while the $O$ in $-OH$ is attached to an $H$ atom. Comparing the next atoms,$C$ $(6)$ > $H$ $(1)$,so $-OCH_3$ has higher priority than $-OH$.$4$. Comparing $-COOH$ and $-CHO$: The $C$ in $-COOH$ is bonded to $(O, O, O)$ (considering double bonds as two single bonds to $O$),while the $C$ in $-CHO$ is bonded to $(O, O, H)$. Comparing the atoms,$-COOH$ has higher priority than $-CHO$.$5$. The final order is $-OCH_3 > -OH > -COOH > -CHO$.

What is the priority order of the groups $-OH, -COOH, -CHO, -OCH_3$ attached to a chiral carbon according to the $Cahn-Ingold-Prelog$ $(CIP)$ sequence rules?

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