The onset of metaphase is marked by the...

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(D) Metaphase is the second stage of mitosis. The onset of metaphase is characterized by the complete disintegration of the nuclear envelope and the n

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complete disappearance of the nuclear envelope and nucleolus.

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(D) Metaphase is the second stage of mitosis. The onset of metaphase is characterized by the complete disintegration of the nuclear envelope and the nucleolus. This allows the spindle fibers to attach to the kinetochores of the chromosomes,which then align at the metaphase plate (equatorial plane).

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