Excess secretion of mineralocorticoids,which | vedclass

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(B) Conn's syndrome (also known as primary hyperaldosteronism) is a condition caused by the excessive production of the hormone aldosterone by the adr

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Conn's syndrome

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(B) Conn's syndrome (also known as primary hyperaldosteronism) is a condition caused by the excessive production of the hormone aldosterone by the adrenal glands.Unlike secondary hyperaldosteronism,which is triggered by the $Renin-Angiotensin-Aldosterone$ system $(RAAS)$,Conn's syndrome is typically caused by an adrenal tumor (adenoma) or hyperplasia,making it independent of the $RAAS$ pathway.This leads to high blood pressure,low potassium levels $(hypokalemia)$,and metabolic alkalosis.

Excess secretion of mineralocorticoids,which is independent of the $Renin-Angiotensin-Aldosterone$ system,results in:

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$I.$ The adrenal cortex secretes many hormones called corticoids.
$II.$ Corticoids involved in carbohydrate metabolism are called glucocorticoids.
$III.$ Cortisol is the main glucocorticoid.
$IV.$ Aldosterone is the main mineralocorticoid.
Select the correct combination from the given options.

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