Sickle-cell anemia is caused by a change in w | vedclass

Name: Exam Paper Generator | JEE NEET Paper Generator | Vedclass
Brand: Vedclass
Rating: 5 (35 reviews)

Question

(B) Sickle-cell anemia is an autosome-linked recessive trait that can be transmitted from parents to the offspring when both the partners are carriers

Vedclass · Accepted Answer

Change in amino acids in the $\beta$-chain of hemoglobin

Vedclass · Answer

(B) Sickle-cell anemia is an autosome-linked recessive trait that can be transmitted from parents to the offspring when both the partners are carriers for the gene. This disease is controlled by a single pair of allele,$Hb^A$ and $Hb^S$. The defect is caused by the substitution of Glutamic acid $(Glu)$ by Valine $(Val)$ at the sixth position of the $\beta$-globin chain of the hemoglobin molecule. This substitution occurs due to the single base pair substitution at the sixth codon of the $\beta$-globin gene from $GAG$ to $GUG$.

Sickle-cell anemia is caused by a change in which of the following?

Similar Questions

Haemophilia is:

Which one is a sex-linked disease?

Which of the following disorders is an autosomal recessive disorder?

From the following pedigree chart of a family,one can make an analysis that:

Thalassaemia is:

Vedclass Test Series

Exam Paper Generator

Online Exam Module