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(D) During the process of oxidative phosphorylation in mitochondria,the electron transport system $(ETS)$ is located in the inner mitochondrial membra

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Intermembrane space

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(D) During the process of oxidative phosphorylation in mitochondria,the electron transport system $(ETS)$ is located in the inner mitochondrial membrane.As electrons pass through the complexes of the $ETS$,energy is released and used to pump protons $(H^+)$ from the mitochondrial matrix into the intermembrane space.This creates a high concentration of protons in the intermembrane space,establishing a proton gradient (electrochemical gradient) across the inner mitochondrial membrane.This gradient drives the synthesis of $ATP$ through the enzyme $ATP$ synthase.

In mitochondria,protons accumulate in the ........ .

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