The vaccine for Hepatitis-$B$ is produced from ...........

Match the following and choose the correct option$-$

Column $I$	Column $II$
$(a)$ Eli Lilly	$(i)$ Bacillus thuringiensis
$(b)$ Bt	$(ii)$ Human insulin
$(c)$ Gene therapy	$(iii)$ Meloidogyne incognita
$(d)$ $\text{RNAi}$	$(iv)$ Adenosine deaminase deficiency

Maximum application of animal cell culture technology today is in the production of

What are transgenic bacteria? Illustrate using any one example.

Which of the following is produced using $E. coli$?

Statements related to human insulin are given below. Which statement$(s)$ is/are correct about genetically engineered insulin?
$(a)$ Pro-hormone insulin contains an extra stretch of $C$-peptide.
$(b)$ $A$-peptide and $B$-peptide chains of insulin were produced separately in $E. coli$,extracted,and combined by creating disulfide bonds between them.
$(c)$ Insulin used for treating diabetes was extracted from cattle and pigs.
$(d)$ Pro-hormone insulin needs to be processed for converting into a mature and functional hormone.
$(e)$ Some patients develop allergic reactions to the foreign insulin.
Choose the most appropriate answer from the options given below: