Arrange the steps of the biochemical reaction in sequence:
$I -$ Diffusion of the substrate towards the active site of the enzyme
$II -$ Formation of the transition state structure
$III -$ Release of the product from the active site
$IV -$ Breaking or formation of bonds

• A
  $I \rightarrow IV \rightarrow III \rightarrow II$
• B
  $IV \rightarrow I \rightarrow III \rightarrow II$
• C
  $I \rightarrow IV \rightarrow II \rightarrow III$
• D
  $I \rightarrow II \rightarrow IV \rightarrow III$