(D) $Al_2O_3$ is an amphoteric oxide (those oxides which show both the properties of acids and bases),so it can react both with acids and alkalis,e.g.

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(D) $Al_2O_3$ is an amphoteric oxide (those oxides which show both the properties of acids and bases),so it can react both with acids and alkalis,e.g. $Al_2O_3 + 6HCl \longrightarrow 2AlCl_3 + 3H_2O$ $Al_2O_3 + 2NaOH + 3H_2O \longrightarrow 2Na[Al(OH)_4]$