A: Kornberg enzyme is associated with the rem | vedclass

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Question

(A) The Kornberg enzyme is $DNA$ polymerase $I$. It plays a crucial role in $DNA$ replication by removing $RNA$ primers using its $5^{\prime} \rightar

Vedclass · Accepted Answer

Assertion and Reason both are correct and Reason is the correct explanation of Assertion.

Vedclass · Answer

(A) The Kornberg enzyme is $DNA$ polymerase $I$. It plays a crucial role in $DNA$ replication by removing $RNA$ primers using its $5^{\prime} \rightarrow 3^{\prime}$ exonuclease activity and filling the gaps with $DNA$ nucleotides. It also possesses $3^{\prime} \rightarrow 5^{\prime}$ exonuclease activity,which is responsible for proofreading (removing mismatched bases). Therefore,both the Assertion and the Reason are correct,and the Reason correctly explains why the Kornberg enzyme is associated with primer removal.

$A$: Kornberg enzyme is associated with the removal of primers and thymine dimers.
$R$: $DNA$ polymerase $I$ performs exonuclease activity in $5^{\prime} \rightarrow 3^{\prime}$ and $3^{\prime} \rightarrow 5^{\prime}$ directions.

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$A$: Kornberg enzyme is associated with the removal of primers and thymine dimers.$R$: $DNA$ polymerase $I$ performs exonuclease activity in $5^{\prime} \rightarrow 3^{\prime}$ and $3^{\prime} \rightarrow 5^{\prime}$ directions.