21 trisomy in humans causes | vedclass

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(B) Down's syndrome is a genetic disorder caused by the presence of an extra copy of chromosome $21$ (trisomy $21$).This condition occurs due to the f

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Down's syndrome

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(B) Down's syndrome is a genetic disorder caused by the presence of an extra copy of chromosome $21$ (trisomy $21$).This condition occurs due to the failure of segregation of homologous chromosomes during meiosis,leading to an individual having $47$ chromosomes instead of the normal $46$.Key features include mental retardation,a characteristic facial appearance (such as epicanthal folds),and a protruding tongue.In contrast,Klinefelter's syndrome $(44+XXY)$ and Turner's syndrome $(44+XO)$ are sex-chromosomal disorders,while Patau's syndrome is caused by trisomy of chromosome $13$.

$21$ trisomy in humans causes

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