Identify the correct statement.

In this technique,large quantities of biotechnological products such as antibiotics,vaccines,and enzymes are produced by maintaining and growing only the desired microbes/eukaryotic cells in a sterile environment.

Which of the following methods is not commonly used for introducing foreign $DNA$ into the plant cell?

Select the option that represents the correct sequence of steps in $r-DNA$ technology.
$(1)$ Insertion of $r-DNA$ into the host
$(2)$ Isolation of $DNA$
$(3)$ Ligation of $DNA$ fragment into the vector
$(4)$ Culturing the host cells in a medium at a large scale and extraction of the desired product
$(5)$ Isolation of the desired $DNA$ fragment
$(6)$ Fragmentation of $DNA$ by restriction endonucleases

Give scientific reasons: The products prepared by recombinant $DNA$ technology have to undergo downstream processing.

Give scientific reasons: Hepatitis $B$ and Bird flu $DNA$ vaccines are called Recombinant $DNA$ vaccines.