Match the following columns:

List-$I$	List-$II$
$(a)$ Bacteria	$(1)$ Saccharomyces cerevisiae
$(b)$ Mucor	$(2)$ $Bt$ cotton
$(c)$ Yeast	$(3)$ Penicillium notatum
$(d)$ Transgenic organism	$(4)$ Lactobacillus

Match List-$I$ with List-$II$ :

List-$I$ (Bioactive molecules)	List-$II$ (Importance)
$A$. Streptokinase	$I$. Immunosuppressive agent
$B$. Statins	$II$. Removal of clots from the blood vessels
$C$. Lipases	$III$. Blood cholesterol-lowering agent
$D$. Cyclosporin $A$	$IV$. Detergent formulations

Match the following columns:

Column $I$	Column $II$
$1.$ $LAB$	$a.$ Quantum $-4000$
$2.$ $Propionibacterium$ $shermanii$	$b.$ Free-living $N_2$-fixer
$3.$ $Acetobacter$ $aceti$	$c.$ Lactic acid production
$4.$ $Clostridium$ $butylicum$	$d.$ Swiss cheese
$5.$ $Pseudomonas$	$e.$ Biogas
$6.$ $Azospirillum$	$f.$ Acetic acid
	$g.$ Butyric acid

$Assertion (S)$: Ernest Chain and Howard Florey were awarded the Nobel Prize in $1948$.
$Reason (R)$: Lactic acid is produced by the fungus $Aspergillus$ $niger$.

Read the following four statements $(A-D)$.
$(A)$ Colostrum is recommended for the new born because it is rich in antibodies.
$(B)$ Chikungunya is caused by a Gram-negative bacterium.
$(C)$ Tissue culture has proved useful in obtaining virus-free plants.
$(D)$ Beer is manufactured by distillation of fermented grape juice.
How many of the above statements are wrong?

The fruit juices turn bitter in taste if they are kept in open place for some time,because of