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(C) Erythrocytes (Red Blood Cells) require specific factors for their maturation in the bone marrow.Vitamin $- B_{12}$ (Cyanocobalamin) and Folic acid

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Vitamin $- B_{12}$

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(C) Erythrocytes (Red Blood Cells) require specific factors for their maturation in the bone marrow.Vitamin $- B_{12}$ (Cyanocobalamin) and Folic acid are essential for $DNA$ synthesis and the maturation of red blood cells.$A$ deficiency of Vitamin $- B_{12}$ leads to pernicious anemia,where the red blood cells are immature and large (megaloblastic).Therefore,Vitamin $- B_{12}$ is a critical factor for the maturation of erythrocytes.

One of the factors required for the maturation of erythrocytes is . . . . . . .

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