Polypeptide chains present in insulin are lin | vedclass

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Question

(B) Insulin is a peptide hormone composed of two short polypeptide chains: chain $A$ and chain $B$.These two chains are linked together by inter-chain

Vedclass · Accepted Answer

Disulphide bridges

Vedclass · Answer

(B) Insulin is a peptide hormone composed of two short polypeptide chains: chain $A$ and chain $B$.These two chains are linked together by inter-chain disulphide bridges (disulphide bonds) between specific cysteine residues.In humans,insulin is synthesized as a pro-hormone (pro-insulin),which contains an extra stretch called the $C$-peptide.During maturation,the $C$-peptide is removed to form mature insulin,leaving the $A$ and $B$ chains connected by disulphide bridges.

Polypeptide chains present in insulin are linked together by...

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