When and where was the word "biotechnology" used for the first time?

The two main techniques that gave birth to modern biotechnology are
$I.$ Chemical engineering
$II.$ Genetic engineering
$III.$ Human genome engineering
$IV.$ Molecular biology
Choose the correct option.

Select the correct option for $r-DNA$.

Which technology involves altering the chemistry of genetic material ($DNA$ and $RNA$) to introduce it into host organisms and thus change the phenotype of the host organism?

How is Genetic Engineering better than hybridization?

Genetic engineering means