The best HLA (human leucocyte antigen) match | vedclass

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(C) For a successful organ or tissue transplant, the $HLA$ (human leucocyte antigen) matching is crucial to prevent graft rejection. $1$. Identical tw

Vedclass · Accepted Answer

Twin  >  sibling  >  parent  >  unrelated donor

Vedclass · Answer

(C) For a successful organ or tissue transplant, the $HLA$ (human leucocyte antigen) matching is crucial to prevent graft rejection. $1$. Identical twins (monozygotic twins) share the exact same genetic makeup, making them the best possible match. $2$. Siblings are the next best choice because they share $50\%$ of their genes with the recipient on average. $3$. Parents are the third choice, as they also share $50\%$ of their genes with the offspring, but the genetic diversity is often higher compared to siblings. $4$. Unrelated donors are the least preferred due to the high probability of $HLA$ mismatch. Therefore, the order of preference is: $Twin  >  Sibling  >  Parent  >  Unrelated 	ext{ donor}$.

The best $HLA$ (human leucocyte antigen) match for transplant in order of preference is:

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