In the following compound,the favourable site | vedclass

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(B) Protonation occurs at the site where the lone pair of electrons is most available for donation to a proton $(H^+)$.In adenine,the nitrogen atoms a

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$b, c$ and $d$

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(B) Protonation occurs at the site where the lone pair of electrons is most available for donation to a proton $(H^+)$.In adenine,the nitrogen atoms at positions $b, c,$ and $d$ have lone pairs that are not involved in the aromatic sextet of the rings.Specifically,the nitrogen at position $d$ is the most basic site because its lone pair is in an $sp^2$ orbital and is not involved in the aromatic system,making it highly available for protonation.Protonation at $b, c,$ or $d$ results in a conjugate acid that is stabilized by resonance.The exocyclic $-NH_2$ group $(a)$ has its lone pair involved in resonance with the ring,and the $-NH-$ group $(e)$ has its lone pair involved in the aromaticity of the imidazole ring,making them less basic.Thus,the favourable sites for protonation are $b, c,$ and $d$.

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