Give differences : Haemophilia and Sickle-cel | vedclass

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Haemophilia
			Sickle-cell Anaemia
		
		
			$(1)$ It occur due to a defective recessive allele present on the $X$-chromosome.
			$(1)

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Haemophilia
			Sickle-cell Anaemia
		
		
			$(1)$ It occur due to a defective recessive allele present on the $X$-chromosome.
			$(1)$ It occurs due to point mutation i.e. a single base pair change leads to a change in amino acid.
		
		
			$(2)$ The defective allele produce nonfunctional protein which later form a non-functional protein which later form a non-functional cascade of protein involving in blood clotting
			$(2)$ In this glutamic ($Glu$) acid is replaced by Valine ($Val$) at sixth position of beta globin chain of haemoglobin molecule.
		
		
			$(3)$ It is a sex-linked recessive disorder.
			$(3)$ It is an autosomal linked recessive disorder.
		
		
			$(4)$ More males are affected than females.
			$(4)$ Both males and females are affected equally.

Give differences : Haemophilia and Sickle-cell Anaemia

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Haemophilia	Sickle-cell Anaemia
$(1)$ It occur due to a defective recessive allele present on the $X$-chromosome.	$(1)$ It occurs due to point mutation i.e. a single base pair change leads to a change in amino acid.
$(2)$ The defective allele produce nonfunctional protein which later form a non-functional protein which later form a non-functional cascade of protein involving in blood clotting	$(2)$ In this glutamic ($Glu$) acid is replaced by Valine ($Val$) at sixth position of beta globin chain of haemoglobin molecule.
$(3)$ It is a sex-linked recessive disorder.	$(3)$ It is an autosomal linked recessive disorder.
$(4)$ More males are affected than females.	$(4)$ Both males and females are affected equally.